50
0.05%
Euphoria, talkativeness, relaxation
100
0.1 %
Central nervous system depression, nausea, possible vomiting, impaired motor and sensory function, impaired cognition
>140
>0.14%

Decreased blood flow to brain
300
0.3%
Stupefaction, possible unconsciousness
400
0.4%
Possible death
>550
>0.55%
Death
The long term effects of to much alcohol are developing alcoholism, cardiovascular disease, malabsorption, chronic pancreatitis, alcoholic liver disease, and cancer. Also Damage to the central nervous system and peripheral nervous system. Ethanol is mostly an agonist and alcohol addiction is the biggest obstacle when overcoming its abuse. Detox is only required in very extreme cases.
In short ethonol is a stupid drug. If you are going to do a drug anyways pick a safer one.
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